While countries are locked in quarantine conditions and the lives of billions have been disrupted, celebrities have joined hands to announce the end of Coronavirus’s crippling disease with the discovery of the vaccine. But there’s another scary scenario: don’t get vaccinated at all. The result of this scenario will be that hope will be created again and again, because the proposed solutions will fail before reaching the final stage. Instead of destroying Quaid-19, people are learning how to live with it. “Cities will reopen slowly and some freedoms will be restored, but in the short term, if experts have advice, it should be followed,” Rob Pichta wrote in a report in Cyanide. Exercise and physical observation will be a part of our lives in the short term, but in many countries, each of them may come up with a sudden instruction on self-cancer. Therapies are being developed, but the spread of the disease can occur every year and the death toll rises year on year. This is a path usually taken by politicians, politicians who are optimistic about human efforts to discover a vaccine. But the lack of vaccine detection is likely to be considered by many experts as a serious option, as it has been the case before.

“There are some viruses whose vaccines have not yet been discovered,” said Dr David Nabarro, a professor of global health at Imperial College London who is studying to be a Special Representative of the World Health Organization. “We can’t make the absolute assumption that a vaccine will not be produced, or if it is, it will successfully pass all the test and safety steps,” he added.

“It is imperative that all communities be prepared to recognize the virus as a permanent and sustainable enemy and to be able to resume their social and economic life,” Nabaru told the Syrians.

Most experts remain hopeful that the Cuvid-19 vaccine will finally be discovered because unlike HIV and malaria, the virus does not mutate quickly. Many, including Dr Anthony Faucchi, director of the National Organization for Allergy and Infectious Diseases, have estimated that this will eventually happen in a year to 18 months. Other figures, such as Chris Whitey, director of the UK’s Department of Health, are considering a more far-reaching perspective and believe that it will take more than a year to develop the Covid-19 vaccine. But if the vaccine is discovered, its realization in any time frame is a great achievement that has never been seen before.

“We will not get the vaccine earlier than 18 months,” Dr Peter Hutter, vice chancellor for the National School of Equatorial Medicine at Houston University Medical Center, told Cyanide. “This does not mean that it is impossible, but if it happens in less than 18 months, it is a masterpiece and a heroic deed,” he added. “We need a master plan and an alternative plan,” he said.

If the vaccine does not work

In 1984, Margaret Heckler, Minister of Health and Human Services, announced at a news conference in Washington that scientists had successfully identified a virus that would later be called HIV, and in less than two years the vaccine would be ready for testing and then mass production. Was. Nearly four decades and 32 million deaths, the world is still waiting for the HIV vaccine. Instead of succeeding, Heckler’s claim was met with widespread pain and death among some people in the West. For years, a positive diagnosis was not only a death sentence but also a reassurance from the patient that the last months of his life should be spent in isolation; At the same time, medical journals have debated whether it is worthwhile to try to save the lives of these patients.

The research did not end in the 1980s. In 1997, then-President Bill Clinton came up with a new challenge: the HIV vaccine will be discovered in the next decade. Fourteen years ago, however, scientists said that we were still 10 years away from the discovery of the vaccine.

Problems with finding the HIV / AIDS vaccine began in their very nature. The flu can change from year to year, so a natural infection or immunization last year will not infect you for years to come. “HIV does its job during an infection,” said Paul Afit, a paediatrician and infectious disease specialist who helped develop the rotavirus vaccine (severe diarrhoea in children). “It’s mutating inside your body, and it means you’re infected with thousands of thousands of HIV viruses, and while it’s mutating, it’s paralyzing your immune system,” Afit told reporters.

AIDS has many unique problems, but Cuvid-19 does not have this level of surprise, which is why many are optimistic about finding a vaccine. But there are other diseases that have confused both scientists and the human body. An effective vaccine for dengue fever, which the World Health Organization says infects 400,000 people a year, has yet to be found and doctors and researchers have been vaccinated. In 2017, production was halted despite widespread efforts to detect the vaccine, which has exacerbated the patient’s condition. Similarly, vaccine production for rhinoviruses and adenoviruses, which, like the coronavirus, can cause cold symptoms, has been difficult to detect. In this regard, there is only one vaccine for adenovirus that is not commercially available.

Explaining the painful and slow process of vaccine production, Nabaru said, “You have high hopes, but all of a sudden all of a sudden they go to waste.” “We are dealing with biological systems, not mechanical systems,” he added. “It really depends on how the body reacts.”

Humanitarian efforts have already begun at Oxford University in the United Kingdom to detect the Coronavirus vaccine and have been tested on chimpanzees. In the United States, different vaccines have been developed by Moderna. “We are currently in the testing phase, not the development phase, and the discovery process has been high and low,” Hutz, who co-produced the SARS vaccine, told Cyanide. “The difficult stage of vaccine production is to see if the worker falls and whether it is safe at all.”

Alternative design

If the same fate befell the Cuvid-19 vaccine, the virus could stay with us for years. But the medical response to the AIDS virus, while still unabated, has provided a framework for living with it. “In the HIV virus, we have been able to make it a chronic disease with antivirals,” says Afit. “That’s what we hope to do with cancer.” “The disease is no longer as punitive as it was in the 1980s,” Afit added. Significant progress in the production of contraceptive pills since then has saved hundreds of thousands of lives from the deadly AIDS epidemic. So far, a number of treatments have been tested for Quaid-19 disease, as scientists are looking for alternatives in parallel with the discovery of the vaccine, and all of these experiments are in their early stages. Scientists are looking for anti-metabolic drug experiments with “remdesivir”, while treatment with blood plasma has also been tested. Hydrosky Chloroquine, known by Donald Trump as the “game-changer”, has not yet responded well to many patients.

“Current drugs are our best candidates,” said Dr Keith Neil, a leading professor of epidemiology of infectious diseases at the University of Nottingham. “The problem is that drugs are gradually being tested,” he said.

“Accidental tests need to be controlled,” Neil, who reviews such tests in medical journals, told Sian. “The articles I read show that drugs have not yet been well developed.” Neil points out that some of the drugs have been removed from the playground, and that if one of the drugs is effective on Covid-19, it will probably be in the coming weeks. The US Food and Drug Administration, however, says one of the drugs has been imported. Remdesivir has had a positive effect on patients and has speeded up their recovery.

If a drug can significantly reduce the number of intensive care units, the drug can be heroically effective, as it can reduce the capacity of hospitals in the intensive care unit and increase the willingness of governments to reopen society sooner. But how effective treatment can depend on which drug has the least side effects. Remdesivir has not been developed internationally, and mass production may be difficult. While the drug may not be an obstacle to the recurrence of the infection, it does mean that coronavirus can be more easily managed, while over the years we will be able to coexist with the disease.

What is it like to live without a vaccine?

If the vaccine is not produced, life will not be the same. We may not be able to get back to our normal lives quickly. “This holiday is not economically and politically tolerable,” says Neil. “So we have to control it in other ways.”

This means that countries want to get rid of this crippling situation as soon as possible, but experts will look for ways to make sure they can buy a definitive cure while life goes on. This means that a new way of life may prevail for months or even years before the disease is permanently eradicated by a vaccine. “It’s very important to cope with Quaid-19,” says Nabaru.

He speaks of new social conventions for citizens of each country, stating that while pursuing a normal life, people should take responsibility for their self-harm if they develop Quaid-19 disease, or always consider the possibility of contracting the disease. This means that the culture of a mild cough or cold should be changed. Experts also predict that there will be a permanent change in their attitude towards work at home or at work. For at least a few days, telework will be seen as a standard solution for white collars. Factories may update their shift or shift service schedule, and office offices may not be filled unnecessarily.

“This should become a way of behaving publicly and make it part of our personal responsibility,” Nabaru added. “Let’s consider those who are in self-centeredness heroes, not isolated people.” He stressed that we must make a collective pact for survival in order to protect against the virus. Of course, infertility says it will be difficult for poorer countries, so it is important to find solutions to support developing countries, especially politically. Nabaru also refers to refugee settlements and calls them high-risk areas.

“It’s very important to have a public health system that has a tracking system, early on-the-job detection and early detection,” says Hutz. “It’s possible, but at the same time it’s complicated and difficult because we haven’t experienced such things before.” “These systems can allow some social interactions to return,” Hotz added. If the transfer is minimal, in fact, some events, such as sporting events, can be reopened, but even these minimums cannot be permanent, and these minimal reopenings may be reversed by government and public health institutions.

This means that the Premier League, the NFL and other sporting events are unobstructed, at least as long as the players are tested, and if the threats return to their original level, the stadiums will be closed again. Neil points out that in this form of social life, public places are probably one of the last places to reopen. “Governments can reopen restaurants by keeping a social distance,” he said. Some European countries have issued a signal that they will allow restaurants to reopen with less capacity.

At the same time, researchers believe that our attitudes, insights, and beliefs in the postcoron world will undergo a fundamental change. In the postcolonial world, we will be confronted with a kind of ungodly human being in relation to values ​​and norms, whose meaning of life changed during the Corona era and under the influence of personal experiences of crisis, meaninglessness and danger. That is to say, Corona will have a gradual and dramatic impact on the way in which ontological and epistemological thinking of human beings, even in everyday life, as well as in ordinary human beings. Some sociologists point out that a person who has experienced a crisis in the meaning of life will inevitably experience a revolution and a change in his understanding of life or the world of his life and the living world, pointing out that “They want to dominate him from the outside. It will be useless.”

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“In societies where the authorities in public life, including political, social and cultural authorities, have not been able to effectively participate in the crisis and make timely and timely decisions, they may have inadvertently led postcoron to self-esteem and self-reliance,” they said. “Sometimes this self-belief may emerge, even in a radical and abnormal form, and cause the world of life to undergo a fundamental semantic transformation.” These sociologists believe that the concept of kinship and family, the concept of environment, the health of body and mind for humans after Corona is another concept, our human and social environment has undergone significant changes and human health knowledge as a cultural thing in the world. After Corona, it will undergo evolution.

© The Eastern Herald


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